Pizza restaurants

Main Street Pizzeria

4.5 385 reviews 11:00 AM - 09:00 PM 213 W Main St, Pickens, SC 29671, United States

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Main Street Pizzeria, nestled in downtown Pickens, SC, has quickly become a local favorite, and it’s easy to see why. Customers rave about the freshness of the ingredients and the exceptional quality of the pizza. Sarah Karafelis highlights the speedy service, boasting about her large pepperoni and onion pizza that was ready in under 25 minutes. Craig Whyde echoes this sentiment, mentioning how they visit multiple times a week for their delicious calzones, which are generously filled with sauce—a feature not commonly found in many pizzerias.

Consistency seems to be key here, as Tamerah noted in her review two years later that every visit still delights her with perfectly crafted calzones, wings, and cheesy bread. The attentive customer service furthers the appeal, with prompt response times and credit for any mix-ups, as experienced by another satisfied customer, S. C.

While the dining space might be limited, as Tiffany Kirby points out, the quality of the food makes the journey worth it. Her enthusiastic claim of driving over an hour just for their pizzas underscores the passion this pizzeria instills in its patrons. Overall, Main Street Pizzeria is highly recommended for anyone seeking flavorful pizza that doesn’t compromise on quality.

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Amenities & More

Service options

Delivery
Onsite services
Takeout
Dine-in

Popular for

Lunch
Dinner
Solo dining

Dining options

Lunch
Dinner
Dessert
Table service

Amenities

Restroom

Atmosphere

Casual
Quiet

Crowd

Tourists

Note: Amenity details are aggregated from verified visits, the venue's website and Google. They may change without notice. We recommend confirming key details (pet policy, accessibility, reservations) directly with Main Street Pizzeria before visiting.

Reviews for Main Street Pizzeria

4.5

385 reviews

100%

17%

Review highlights

Based on 385 reviews

Main Street Pizzeria in Pickens, SC consistently receives praise for its high-quality, fresh ingredients and flavorful menu offerings, including pizzas, calzones, cheese bread, and wings. Customers appreciate the quick preparation and efficient service, with orders often ready in a timely manner. The staff is frequently described as friendly and attentive, contributing positively to the overall experience. While the establishment currently lacks a dedicated dining area, this does not detract from its appeal, as many visitors highlight the convenience and reliability of both takeout and delivery options. Cleanliness and order accuracy further enhance customer satisfaction. Overall, Main Street Pizzeria stands out as a dependable local favorite renowned for excellent food and welcoming service, making it a top choice for residents and newcomers alike seeking quality pizza in a casual setting.

Sarah Karafelis

Jun 29, 2025

If your in downtown pickens give this place a try! Ordered a large pep and onion and a small cheese for the kids. 22 and 15 minutes CANT BEAT THAT! Also when you walk in its one of the cleanest pizza shops ive been to. The guy who took my order was nice and got it right the first time which seems to be a rarity lately,it was refreshing.

Craig Whyde

Jun 27, 2025

This place was a huge surprise! The pizza hut is closed down across the street so we decided to give this place a try... boy I'm so glad we did. The pizza is fresh made from fresh ingredients. We order or come in at least 2x even sometimes 3-4x a week! The calzones are to die for. Alot of places dont add sauce on the inside... but they do! You will not be let down here! Great folks too.

Tamerah

Jun 08, 2025

Adding to my review 2 years later. Main Street pizza is still as fantastic as the first time I ordered. Pizza, calzones, cheeses bread, wings all delicious every time. The delivery drivers are also very pleasant. Delivery was excellent and food was great. New in town and very happy I found an incredible pizza joint that delivers to me all the way in the hills

S. C

May 25, 2025

I ordered food from here the other night. It was our first time. It was easy to order over the phone. I didn't need to wait forever to get through. That was nice. I had my food picked up by a family member. He didn't know what all I ordered (my fault). When he got home we were missing a salad so I called up and they said they would give that back as a credit. I didn't check, but I will. I was happy with that and the customer service previously. The food was good too. I liked the wings we ordered.

tiffany Kirby

Apr 30, 2025

Right now they don't really have a dining area so there's not much as far as atmosphere.. but if you want the best pizza you've ever eaten, you need to come here. Great customer service and even better food. I would drive over an hour just to get one of their pizzas, probably farther. If you've never been here you definitely need to come

Paul DeMarco

Apr 19, 2025

We got a pizza and breadsticks. It was priced a little high but overall delicious. I recommend this place and would return.

Gary Green

Apr 14, 2025

Got my pizza to go. Called it in and picked it up there. It was a great pizza good ingredients and baked nicely. I will definitely eat from there again!

Dustin L

Mar 12, 2025

I am a pizza king, meaning I love pizza. I had a pizza from here today for the first time & it was incredibly outstanding & extremely cheap. It was like a NY Style without the fat crust on back. I am well on my way to having a snaccident where I accidentally eat the whole thing. I live an hour away, but I will be back tomorrow.